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Kristina’s family has a certain star power. Three years ago, a program on Russian state television, “Vesti,” called Kristina "a million dollar baby." Kristina's long blonde hair, sometimes curled or fixed up in a bun like an adult, her puffy childish cheeks and lips often covered in make-up, have appeared on the cover of Vogue Bambini, and shined for Dolce & Gabbana, Benetton, and Armani. The Pimenova sensation has been growing for a while. (Ironically, perhaps, this video segment is posted on Kristina’s Facebook page.) “It just becomes dangerous,” said Shields. But Shields said she was concerned about the social media environment today, which spreads the images so far and fast, and often with disturbing anonymous comments. “I don’t think they’re that bad, these photos,” Shields told Meredith Viera. And while the “beautiful” is evident, especially those penetrating grey-blue eyes, there’s an uncomfortable edge to some of the photographs that blurs the difference between “girl” and “woman.”īrooke Shields, 49, who started modeling when she was less than a year old, posed nude when she was ten, and played a child prostitute in the Louis Malle film “Pretty Baby” when she was 12, recently said she didn’t think the pictures of Pimenova she’d seen were particularly suggestive.
#IMAGEZILLA LS PM FULL#
One fashion blog named her recently as “the most beautiful girl in the world,” full stop. She’s probably a very likeable kid, in fact, but the popularity is all about the pictures.
#IMAGEZILLA LS PM TRIAL#
In instances in which a randomized clinical trial is not feasible, natural history and other observational cohort studies need to be as carefully designed and reported as the classic randomized clinical trial, to yield useful information.MOSCOW - Do you know any children with 2,500,000 “likes” on their Facebook pages? A nine-year-old Russian girl living in Moscow, Kristina Pimenova, just topped that number. We should strive toward a comparable level of quality of evidence in surgical treatment of knee injuries. In evaluating medical treatment, we now expect large randomized clinical trials complemented by postmarketing monitoring. A better understanding of these variables may improve future prevention and treatment strategies. Variation in outcome is reinforced by additional variables associated with the individual such as age, sex, genetics, obesity, muscle strength, activity, and reinjury. Osteoarthritis development in the injured joints is caused by intra-articular pathogenic processes initiated at the time of injury, combined with long-term changes in dynamic joint loading. A consistent finding in a review of the literature is the often poor reporting of critical study variables, precluding data pooling or a meta-analysis. There is a lack of evidence to support a protective role of repair or reconstructive surgery of the anterior cruciate ligament or meniscus against osteoarthritis development. These individuals make up a substantial proportion of the overall osteoarthritis population. At 10 to 20 years after the diagnosis, on average, 50% of those with a diagnosed anterior cruciate ligament or meniscus tear have osteoarthritis with associated pain and functional impairment: the young patient with an old knee.

Injuries of the anterior cruciate ligament and menisci are common in both athletes and the general population. The objectives of this study are to review the long-term consequences of injuries to the anterior cruciate ligament and menisci, the pathogenic mechanisms, and the causes of the considerable variability in outcome.
